Next Sleep

2 sold in last 8 hours
60 Capsules
Natural Promotion Of Quality Sleep
$34.99
customers are viewing this product
https://cdn.shopify.com/s/files/1/0295/5303/3260/t/3/assets/NextSleepWomen-1580300472843.jpg
https://cdn.shopify.com/s/files/1/0295/5303/3260/t/3/assets/NextSleepMan-1580300621509.jpg
https://cdn.shopify.com/s/files/1/0295/5303/3260/t/3/assets/sleepcouplepro-1582789254347.png
https://cdn.shopify.com/s/files/1/0295/5303/3260/t/3/assets/sleep24-1583199334141.jpg
×

Next Sleep is a formulary blend of botanicals, nutrients, neurotransmitters, and neurotransmitter precursors designed to support quality sleep and the promotion of calming brain activity. Next Sleep promotes GABAnergic and seritonergic activity, supporting the ability to get to sleep, and stay asleep. Now clinicians can attain all of the various interventions typically used in natural promotion of quality sleep in one product, improving patient convenience and compliance.

Key Ingredients of Next Sleep
Next Sleep contains valerian root (Valeriana officinalis), passion flower (Passiflora incarnata), and lemon balm (Melissa officinalis), all safe nervine botanicals known for their relaxant properties and ability to reduce tension and promote sleep, without causing morning grogginess.
Valerian root has demonstrated sedative effects due to its ability to induce the release of GABA from brain tissue. It has been suggested that the passion flower and German chamomile (Matricaria recubita) constituent apigenin binds to central ben-zodiazepine receptors, possibly causing anxiolytic effects (anxiety reducing) without impairing memory, diminishing mo- tor skills, or causing drowsiness upon awakening. Lemon balm has been suggested to improve calmness via the inhibitory action of GABA, similar to benzodiazepine, but without the overt side-effects of these medications. Direct stimulation of Gamma aminobutyric acid (GABA), the main calming neurotransmitter in the body, is provided with a new form of GABA known as PharmaGABATM, a proprietary material naturally manufactured via a fermentation process and considered more effective than other traditional, chemically produced synthetic forms. In addition, support of calming neurotransmitter pro- duction is provided with the inclusion of L-theanine, clinically proven to reduce stress and improve the quality of sleep.
Next Sleep also includes melatonin, a multifunctional hormone whose main role lies in its involvement in the control of the circadian (day/night) biological rhythms. Melatonin mediates the body's response to variations of natural light availabil- ity from indoor/outdoor exposure or due to seasons (winter/summer). Darkness into the eye tells the brain to make melatonin so the body can prepare for sleep mode. Its production should peak at night and it is instrumental for maintaining quality sleep patterns. Melatonin production declines significantly with age, often causing sleep difficulties associated with aging. Supplemental melatonin was shown in studies to help with falling asleep when taken about 30 minutes before the desired sleep time. The most common dose found effective for sleep was 3mg.
5-HTP can be used in conjunction with melatonin, as a precursor to serotonin, which can further support endogenous mela- tonin production during the night to help with staying asleep. When using 5-HTP for enhancing serotonin and melatonin production to promote healthy mood and sleep, the addition of the synergistic nutrient pyridoxal-5-phosphate, an activated form of vitamin B6, is suggested to catalyze the conversion of 5-HTP to serotonin (5-HT).

Suggested Dosage: Take 2 capsules, 30 to 60 minutes prior to bedtime, or as directed by your health care practitioner.

Who should take Next Sleep?
Next Sleep is ideal for those experiencing difficulty getting to sleep, or staying asleep through the night.

Caution with GABA
Due to the inclusion of GABA, this product is not recommended for pregnant or lactating women, as well as young children, unless under the guidance of a health care practitioner.

Conditions for which melatonin is not recommended:
• Autoimmune conditions such as lupus or arthritis, because the
immune stimulatory effect of melatonin may exacerbate the action of certain types of lymphocytes or B-cells involved in the pathogenic course of these diseases
• Immune-related cancers such as lymphoma and leukemia
• Pregnancy, lactation or during the time where fertility is desired

Interactions with drug therapy
Melatonin and 5-HTP may not be suitable to administer along with SSRI and MAOI medications and corticosteroid therapy. Please discuss this with your health care provider before using InsomnitolTM with these medication classes.

References:
1. Valerian. Hadley S, Petry JJ. Am Fam Physician 2003;67:1755-1758.
2. On the spasmolytic activity of valeriana extracts (author’s transl). Wagner H, Jurcic K. Planta Med 1979;37:84-86. [Article in german]
3. Valeriana officinalis Monograph.. Altern Med Rev 2004 Dec;9(4):438-41.
4. Passiflora: a review update. Dhawan K, Dhawan S, Sharma A. J Ethnopharmacol 2004 Sep;94(1):1-23.
5. Passion flower (Passiflora incarnata L.)-a reliable herbal sedative. Wien Krenn L. Med Wochenschr 2002;152(15-16):404-6. [Article in German] 6. Attenuation of laboratory-induced stress in human after acute administration of Melissa officinalis (Lemon Balm). Kennedy DO, Little W, Sc-

holey AB. Psychosom Med 2004 Jul-Aug;66(4):607-13.
7. Plants and the central nervous system. Carlini EA. Pharmacol Biochem Behav 2003 Jun;75(3):501-12
8. Flavonoids from lemon balm (Melissa officinalis L., Lamiaceae). Patora J, Klimek B. Acta Pol Pharm 2002 Mar-Apr;59(2):139-43.
9. Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Awad R, Arnason JT,

Trudeau V, et al. Phytomedicine 2003 Nov;10(8):640-9.
10. L-Theanine reduces psychological and physiological stress responses. Kimura K, Ozeki M, Juneja L, Ohira H (2007). Biol Psychol 74 (1):

39–45.
11. Sleep-inducing effects of low doses of melatonin ingested in the evening. Zhadanova IV, Wurtman RJ, Lynch HJ, et al. Clin Pharmacol Ther

1995;57:552-8.
12. The role of melatonin and circadian phase in age-related sleep maintenance insomnia: assessment in a clinical trial of melatonin replacement.

Hughes RJ, Sack RL, Lewy AJ. Sleep 1998;21:52-68.
13. A double-blind trial of melatonin as a treatment for jet lag in international cabin crew. Petrie K, Dawson AG, Thompson L, et al. Biol Psychiatry

1993;33:526-30.
14. Textbook of Natural Medicine (2nd Ed.). Pizzorno JE, Murray MT. Churchill Livingstone, New York, 1999.
15. Complimentary & Alternative Medicines: Professional’s Handbook. Fetrow CW, Avila JR. Springhouse, Springhouse, PA, 1999.
16. Botanical Influences on Illness: A sourcebook of clinical research. Werbach MR, Murray, MT. Third Line Press, Tarzana, California, 1994. 17. Incorporating Herbal Medicine Into Clinical Practice. Bascom A. F.A. Davis Co., Philadelphia, 2002.
18. Encyclopedia of Herbal Medicine. Cheallier A. Dorling Kindersley, London, 2000.
19. Pharmacognosy and Pharmacobiotechnology. Robbers JE, Speedie MK, Tyler VE. Williams & Wilkins, Baltimore, 1996.
20. PDR for Nutritional Supplements, 1st Ed. Medical Economics/Thompson Healthcare, 2001.
21. PDR for Herbal Medicines, 1st Ed. Medical Economics/Thompson Healthcare, 1998.

×
https://cdn.shopify.com/s/files/1/0295/5303/3260/t/3/assets/ScreenShot2019-12-18at120855PM-1580300621504.png

Customer Reviews

Based on 33 reviews Write a review
[time] minutes ago, from [location]
Next Sleep
You have successfully subscribed!
ico-collapse
0
Recently Viewed
ic-cross-line-top
Top
ic-expand
ic-cross-line-top